Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon- Antibody, in Patients With Discoid Lupus Erythematosus [skin]

GSE100093

Homo sapiens

60 Downloadable Samples

Affymetrix HT HG-U133+ PM Array Plate (hthgu133pluspm)

Submitter Supplied Information

Description

This is a phase I randomized, double-blind, placebo-controlled crossover study which sought to evaluate a single dose of AMG 811, an anti-IFN antibody, in patients with DLE.

PubMed ID

28118537

Publication Title

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus.

Total Samples

Submitter’s Institution

Amgen Inc.

Authors

Werth VP, Fiorentino D, Sullivan BA, Boedigheimer MJ, Chiu K, Wang C, Arnold GE, Damore MA, Bigler J, Welcher AA, Russell CB, Martin DA, Chung JB

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-100093

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