Expression data comparing Normal Human Bronchial Epithelial Cells (NHBE) cells in states of senescence, proliferation and quiescence

EGFR inhibitor Erlotinib treatment can induce NHBE into profound cell cycle arrest that include senescence and quiescence. Because senescent cells feature high senescence assocaited-beta-galactosidase(SA--gal) activty, which has been used as marker for FACS based collection of senescent and quiescent cells, respectively.

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Yuan L, Zhai L, Qian L, Huang, Ding Y, Xiang H, Liu X, Thompson JW, Liu J, He YH, Chen XQ, Hu J, Kong QP, Tan M, Wang XF