Illumina sequencing of library 9645643, constructed from sample accession ERS420088 for study accession ERP016356.  This is part of an Illumina multiplexed sequencing run (12391_1).  This submission includes reads tagged with the sequence ATCACGTT.

Illumina HiSeq 2000 paired end sequencing

Schistosoma mansoni ovaries, single sex infection

Schistosoma mansoni

Characterising the transcriptome profiles of adult ovaries and adult testes, aiming to unravel signal transduction cascades involved in e.g. gametogenesis and/or vitellogenesis.

Study description:	This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ Schistosomes are blood dwelling digenean trematodes that mature as adults in the intestinal or urinary veins, predominantly of mammals. Adult female Schistosomes produce eggs of which approximately 40% fail to pass into faeces or urine (species-dependent) but are dispersed by the blood stream into different organs where they provoke severe inflammation. This parasitic infection is known as schistosomiasis and considered by the WHO as the second most socioeconomically devastating parasitic disease, next only to malaria, with hundreds of millions infected worldwide. As the eggs represent the causative pathogenic agents, the understanding of egg forming processes, and therefore of the schistosomal reproductive biology in general, is of fundamental interest. Additionally the differences between immature (pre-mating) and mature (post-mating) adult worms are of significant interest; adults only reach maturity upon mating. Trasncriptomic sequencing of gonad-specific cellular material will help to unravel signal transduction cascades involved in e.g. gametogenesis and/or vitellogenesis. This project aims to characterize the transcriptome profiles of immature and mature adult ovaries and adult testes.

S__mansoni_male_and_female_adult_worm_reproductive_organs_pre__and_post_pairing

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