Illumina sequencing of library 15128366, constructed from sample accession ERS874706 for study accession ERP012527.  This is part of an Illumina multiplexed sequencing run (18122_1).  This submission includes reads tagged with the sequence TCAGGAGG.

Illumina HiSeq 2000 paired end sequencing

Homo sapiens

As mentioned before, the goal of this study consists of depicting the molecular mechanisms by which recently discovered tumor suppressor are able to constraint tumor development.

Transposon mutagenesis screens in mice has allowed us the identification of new tumor suppressor genes in cancer. To further explore the mechanistic role of these genes at the molecular level, we decided to study the transcriptome of human immortalized and cancer cells which underwent siRNA-mediated silencing of these tumor suppressors. 

This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

Identification_and_molecular_charaterization_of_new_tumor_suppressor_genes_on_prostate_cancer

Submitter Supplied Information

Samples