DCM,dilated cardiomyopathy, is a major cause of chronic heartfailure. In this study,128 samples from DCM patients (left ventricle) have been sequenced by RNAseq. We obtained cardiac tissue from 128 subjects with end-stage heart failure. All subjects were transplanted at the Royal Brompton and Harefield NHS Foundation Trust (London, United Kingdom). On this occasion, cardiac samples were obtained and immediately frozen in liquid nitrogen.